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NCRP Report No. 80, Induction of Thyroid Cancer by Ionizing Radiation

NCRP Report No. 80 assesses the potential for cancer induction in the thyroid gland after exposure of the gland to external x and gamma radiation, or internally deposited radionuclides of iodine. Data and assumptions from existing human and animal studies are examined and, where possible, used to develop average risk estimates for combined populations over various ranges of radiation dose to the thyroid. The relative carcinogenicity of various iodine isotopes is examined on the basis of available data. The relative carcinogenicity per unit of absorbed dose of external x or gamma radiation and various iodine isotopes is estimated. A specific model for risk estimation is developed in the Report and utilized in formulating risk estimates which are considered to be applicable to the population of the United States for mean thyroidal doses in the range from 6 to 1,500 rad.

 

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